| Ammo Inventor (25)
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Successfully invented all possible ammo types.
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| Avid Inventor (10)
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Successfully invent at least 100 items.
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| Basic Inventor (5)
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Successfully invent at least one item.
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| Became a Big Daddy (30)
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The player has become a Big Daddy.
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| Bought One Slot (5)
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Purchase one slot in any Plasmid or Tonic track.
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| Brass Balls (100)
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Beat the game on Hard difficulty without using a Vita Chamber.
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| Broke Fontaine's Mind Control (30)
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The player has broken Fontaine's mind control.
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| Completed Cohen's Masterpiece (30)
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The player has completed Sander Cohen's great masterpiece.
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| Completed Welcome (10)
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Successfully complete the Welcome To Rapture Level.
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| Dealt with every Little Sister (40)
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Either Harvest or Rescue every Little Sister in the game.
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| Defeated Andrew Ryan (30)
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The player has defeated Andrew Ryan.
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| Defeated Atlas (100)
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The player has defeated Atlas.
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| Defeated Dr. Steinman (15)
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The player has defeated the crazed Dr. Steinman.
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| Defeated Peach Wilkins (15)
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The player has defeated Peach Wilkins.
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| Five Fully Upgraded Weapons (10)
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Fully upgrade five weapons.
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| Found Cohen's Room (10)
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The player has entered Sander Cohen's personal quarters.
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| Four Fully Upgraded Weapons (10)
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Fully upgrade four weapons.
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| Fully Researched Bouncer (10)
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Fully research the Bouncer.
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| Fully Researched Gun Splicer (10)
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Fully research the Leadhead Splicer.
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| Fully Researched Houdini Splicer (10)
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Fully research the Houdini Splicer.
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| Fully Researched Little Sister (10)
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Fully research the Little Sister.
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| Fully Researched Nitro Splicer (10)
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Fully research the Nitro Splicer.
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| Fully Researched Rosie (10)
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Fully research the Rosie.
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| Fully Researched Spider Splicer (10)
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Fully research the Spider Splicer.
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| Fully Researched Thug Splicer (10)
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Fully research the Thuggish Splicer.
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| Hacked a Safe (10)
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Successfully hack a safe.
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| Hacked a Security Bot (10)
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Successfully hack a security bot.
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| Hacked a Security Camera (10)
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Successfully hack a security camera.
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| Hacked a Turret (10)
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Successfully hack a turret.
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| Hacked a Vending Machine (10)
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Successfully hack a vending machine.
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| Historian (50)
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Find every audio diary.
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| Irony (10)
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The player has taken a picture of Sander Cohen's corpse.
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| Little Sister Savior (100)
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Complete the game without harvesting any Little Sisters.
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| Lucky Winner (10)
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Hit the jackpot at a slot machine.
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| Maxed All Tracks (50)
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Purchased every slot in all four Plasmid and Tonic tracks.
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| Maxed One Track (20)
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Purchased every slot in one of the Plasmid or Tonic tracks.
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| One Fully Upgraded Weapon (5)
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Fully upgrade one weapon.
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| One Successful Hack (5)
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Perform at least one successful hack.
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| Prolific Photographer (5)
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Take at least one photo in every research group.
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| Quality Research Photo (20)
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Take a Research Photo of the highest grade.
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| Research PhD (20)
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Max out all possible research.
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| Researched a Splicer (5)
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Take at least one Research Photo of a Splicer.
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| Restored the Forest (15)
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The player has restored the forests of Arcadia.
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| Seriously Good At This (40)
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Complete the game on the hardest difficulty setting.
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| Skilled Hacker (40)
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Successfully complete 50 hacks.
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| Three Fully Upgraded Weapons (10)
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Fully upgrade three weapons.
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| Toaster in the Tub (10)
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Shock an enemy in the water.
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| Tonic Collector (50)
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Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks.
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| Two Fully Upgraded Weapons (5)
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Fully upgrade two weapons.
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| Upgraded a Weapon (5)
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Acquire at least one weapon upgrade.
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| Weapon Specialist (20)
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Acquire all upgrades for all weapons.
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